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KMID : 0357520140370010015
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Journal of Radiological Science and Technology
2014 Volume.37 No. 1 p.15 ~ p.20
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Development of Biodegradable Polymeric Membrane for Interventional Procedure: Preliminary Study
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Bang Jung-Wan
Hyun Chang-Yong
Kim Tae-Hyung
So Woon-Young
Kim Jin-Tae
Kim Sang-Sub
Jung Hee-Dong
Heo Yeong-Cheol
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Abstract
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This study was to evaluate clinical feasibility of biodegradable polymeric membrane for interventional procedure in preliminary study. Bio-degradable polymetric membrane was produced into a solution by mixing hyaluronic acid powder with NaOH solution in a heating mantle. Three different concentrations of contrast media (10, 20, and 30 vol%) were added to the produced soluble powder, and vertical agitation was performed for 12 hours at a speed of 100 to 200 rpm at a room temperature. It was freeze dried for 24 hours at a temperature$80^{circ}C$ 수식 이미지 . Pressure on the freeze dried sample was exerted by a hydraulic press in order to form the freeze dried sample into a membrane. The membrane produced with varying contrast medium concentration was visually examined by a scanning electron microscope and radiographically inspected. Under the visual examination, the higher the concentration of contrast medium, the rougher the surface. Radiographic transparency was similar under all conditions of fluoroscopic radiography, simple radiography, and serial radiography. In conclusion, this preliminary study verified that bio-degradable membrane produced with hyaluronic acid was a material with clinical usability.
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KEYWORD
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interventional procedure, biodegradable polymeric membrane, hyaluronic acid
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